What’s more, one mouse study from 2010 found that TMG supplements could reverse insulin resistance in the liver. Plus, in an animal study, administering TMG supplements to mice on a high fat diet improved fat metabolism and decreased insulin resistance ( 15). Several studies have found that TMG supplements could improve insulin resistance, a condition that impairs your body’s ability to use the hormone insulin to regulate blood sugar levels ( 13).įor example, a study in nearly 2,400 people associated a higher intake of choline and betaine with decreased insulin resistance ( 14). That’s why more studies are needed before experts can confidently recommend TMG as an athleticism-boosting supplement ( 10, 11, 12). Meanwhile, several other studies show that TMG has no impact on exercise performance or strength. Still, it noted that in two studies, TMG supplements significantly increased muscle strength and power ( 9). increase the synthesis of creatine, a compound that provides energy to your muscle cellsĪnother review of seven studies turned up mixed results.One review reported that TMG supplements could improve body composition and enhance performance in both endurance- and resistance-type exercises ( 8).Īlthough the exact mechanisms are unclear, researchers speculate that TMG may ( 8): Many athletes use TMG supplements with the aim of enhancing exercise performance. Ultimately, more research is needed on how these supplements may affect heart health. On the other hand, some studies - both older and newer - have shown that TMG supplements could increase levels of total and LDL (bad) cholesterol in the blood, both of which are risk factors for heart disease ( 6, 7). Too high levels of this compound can increase your risk of heart disease ( 3).Ī 2013 review of 5 studies showed that taking at least 4 grams of TMG per day for 6 weeks could lower blood levels of homocysteine in healthy adults ( 4).Īnother review had similar findings, noting that taking 4 grams of TMG per day lowered homocysteine levels without negatively impacting other aspects of heart health, like blood pressure or triglyceride levels ( 5). Some research shows that TMG could decrease blood levels of homocysteine, a type of amino acid found in your blood. May lower homocysteine levels to improve heart health TMG supplements may be associated with several health benefits.
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